Background:

LMTK3 (Lemur Tyrosine Kinase 3) is a Protein Coding gene. Among its related pathways are ERK Signaling and Akt Signaling. GO annotations related to this gene include transferase activity, transferring phosphorus-containing groups and protein tyrosine kinase activity. An important paralog of this gene is AATK. rotein kinase which phosphorylates ESR1 (in vitro) and protects it against proteasomal degradation. May also regulate ESR1 levels indirectly via a PKC-AKT-FOXO3 pathway where it decreases the activity of PKC and the phosphorylation of AKT, thereby increasing binding of transcriptional activator FOXO3 to the ESR1 promoter and increasing ESR1 transcription (PubMed: 21602804). Involved in endocytic trafficking of N-methyl-D-aspartate receptors (NMDAR) in neurons (By similarity).

Classification:

Primary antibody

Alternative names:

LMTK3; KIAA1883; TYKLM3; Serine/threonine-protein kinase LMTK3; Lemur tyrosine kinase 3

Species reactivity:

Human;Mouse

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from human LMTK3. AA range:1251-1300

Concentration:

1 mg/ml

Molecular weight:

153661

Applications:

WB, IHC-p, ELISA

Storage:

-20°C for one year

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com