Background:

The leucine zipper down-regulated in cancer 1 encoded by LDOC1 contains a leucine zipper-like motif and a proline-rich region that shares marked similarity with an SH3-binding domain. The protein localizes to the nucleus and is down-regulated in some cancer cell lines. It is thought to regulate the transcriptional response mediated by the nuclear factor kappa B (NF-kappaB). The gene has been proposed as a tumor suppressor gene whose protein product may have an important role in the development and/or progression of some cancers.

Classification:

Primary antibody

Alternative names:

LDOC1; BCUR1; Protein LDOC1; Leucine zipper protein down-regulated in cancer cells

Species reactivity:

Human;Mouse

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from human LDOC1. AA range:21-70

Concentration:

1 mg/ml

Molecular weight:

16968

Applications:

IHC-p, ELISA

Storage:

-20°C for one year

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