Background:

Activator protein-2 alpha (AP-2 alpha) is a developmentally-regulated transcription factor and important regulator of gene expression during vertebrate development and carcinogenesis. Krueppel-like factor 12 encoded by KLF12 is a member of the Kruppel-like zinc finger protein family and can repress expression of the AP-2 alpha gene by binding to a specific site in the AP-2 alpha gene promoter. Repression by the encoded protein requires binding with a corepressor, CtBP1. Two transcript variants encoding different isoforms have been found for this gene.

Classification:

Primary antibody

Alternative names:

KLF12; AP2REP; HSPC122; Krueppel-like factor 12; Transcriptional repressor AP-2rep

Species reactivity:

Human;Mouse

Host:

Rabbit

Isotype:

IgG

Immunogen:

Synthesized peptide derived from the Internal region of human KLF12.

Concentration:

1 mg/ml

Molecular weight:

44240

Applications:

WB, IHC-p, ELISA

Storage:

-20°C for one year

More info:

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