Background:

IRF3 encodes a member of the interferon regulatory transcription factor (IRF) family. The encoded protein is found in an inactive cytoplasmic form that upon serine/threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon-induced genes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Classification:

Primary antibody

Alternative names:

Interferon regulatory factor 3 (IRF-3)

Species reactivity:

Human

Host:

Rabbit

Isotype:

IgG

Immunogen:

Synthetic peptide from human protein at AA range: 279-352

Concentration:

1 mg/ml

Molecular weight:

47219

Applications:

WB, IHC-p, ELISA

Storage:

-20°C for one year

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