Background:

E2F6 encodes a member of a family of transcription factors that play a crucial role in the control of the cell cycle. E2F transcription factor 6 encoded by E2F6 lacks the transactivation and tumor suppressor protein association domains found in other family members, and contains a modular suppression domain that functions in the inhibition of transcription. It interacts in a complex with chromatin modifying factors. There are pseudogenes for this gene on chromosomes 22 and X. Alternative splicing results in multiple transcript variants.

Classification:

Primary antibody

Alternative names:

E2F6; Transcription factor E2F6; E2F-6

Species reactivity:

Human;Mouse;Rat

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from human E2F6. AA range:141-190

Concentration:

1 mg/ml

Molecular weight:

31844

Applications:

WB, IHC-p, ELISA

Storage:

-20°C for one year

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