Background:

The protein encoded by IL16 is a pleiotropic cytokine that functions as a chemoattractant, a modulator of T cell activation, and an inhibitor of HIV replication. The signaling process of this cytokine is mediated by CD4. The product of this gene undergoes proteolytic processing, which is found to yield two functional proteins. The cytokine function is exclusively attributed to the secreted C-terminal peptide, while the N-terminal product may play a role in cell cycle control. Caspase 3 is reported to be involved in the proteolytic processing of this protein. Alternate splicing results in multiple transcript variants.

Classification:

Primary antibody

Alternative names:

IL16; Pro-interleukin-16

Species reactivity:

Human

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from human IL-16. AA range:48-97

Concentration:

1 mg/ml

Molecular weight:

66646

Applications:

IHC-p, ELISA

Storage:

-20°C for one year

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