Background:

HSPA1A encodes a 70kDa heat shock protein which is a member of the heat shock protein 70 family. In conjuction with other heat shock proteins, heat shock protein family A (Hsp70) member 1A stabilizes existing proteins against aggregation and mediates the folding of newly translated proteins in the cytosol and in organelles. It is also involved in the ubiquitin-proteasome pathway through interaction with the AU-rich element RNA-binding protein 1. HSPA1A is located in the major histocompatibility complex class III region, in a cluster with two closely related genes which encode similar proteins.

Classification:

Primary antibody

Alternative names:

HSPA1A; HSPA1; HSPA1B; Heat shock 70 kDa protein 1A/1B; Heat shock 70 kDa protein 1/2; HSP70-1/HSP70-2; HSP70.1/HSP70.2

Species reactivity:

Human

Host:

Rabbit

Isotype:

IgG

Immunogen:

Synthesized peptide derived from human HSP70 around the non-acetylation site of K246.

Concentration:

1 mg/ml

Molecular weight:

70052

Applications:

IF, WB, IHC-p, ELISA

Storage:

-20°C for one year

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