Background:

Heparan sulfate proteoglycans are major components of the basement membrane and extracellular matrix. Heparanase encoded by HPSE is an enzyme that cleaves heparan sulfate proteoglycans to permit cell movement through remodeling of the extracellular matrix. In addition, this cleavage can release bioactive molecules from the extracellular matrix. Several transcript variants encoding different isoforms have been found for this gene.

Classification:

Primary antibody

Alternative names:

HPSE; HEP; HPA; HPA1; HPR1; HPSE1; HSE1; Heparanase; Endo-glucoronidase; Heparanase-1; Hpa1

Species reactivity:

Human

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from the Internal region of human HPSE. AA range:241-290

Concentration:

1 mg/ml

Molecular weight:

61177

Applications:

WB, IHC-p, ELISA

Storage:

-20°C for one year

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