Background:

HOXD10 is a member of the Abd-B homeobox family and encodes a protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox D genes located on chromosome 2. The homeobox D10 functions as a sequence-specific transcription factor that is expressed in the developing limb buds and is involved in differentiation and limb development. Mutations in this gene have been associated with Wilm's tumor and congenital vertical talus (also known as "rocker-bottom foot" deformity or congenital convex pes valgus) and/or a foot deformity resembling that seen in Charcot-Marie-Tooth disease.

Classification:

Primary antibody

Alternative names:

HOXD10; HOX4D; HOX4E; Homeobox protein Hox-D10; Homeobox protein Hox-4D; Homeobox protein Hox-4E

Species reactivity:

Human;Mouse

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from human HOXD10. AA range:291-340

Concentration:

1 mg/ml

Molecular weight:

38411

Applications:

WB, ELISA

Storage:

-20°C for one year

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