Background:

HMGB2 encodes a member of the non-histone chromosomal high mobility group protein family. The proteins of this family are chromatin-associated and ubiquitously distributed in the nucleus of higher eukaryotic cells. In vitro studies have demonstrated that high mobility group protein B2 is able to efficiently bend DNA and form DNA circles. These studies suggest a role in facilitating cooperative interactions between cis-acting proteins by promoting DNA flexibility. This protein was also reported to be involved in the final ligation step in DNA end-joining processes of DNA double-strand breaks repair and V(D)J recombination.

Classification:

Primary antibody

Alternative names:

HMGB2; HMG2; High mobility group protein B2; High mobility group protein 2; HMG-2

Species reactivity:

Human;Mouse;Rat

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from human HMGB2. AA range:131-180

Concentration:

1 mg/ml

Molecular weight:

24034

Applications:

WB, IHC-p, IF, ELISA

Storage:

-20°C for one year

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