Background:

HMGB1 encodes high mobility group protein B1 that belongs to the High Mobility Group-box superfamily. The encoded non-histone, nuclear DNA-binding protein regulates transcription, and is involved in organization of DNA. This protein plays a role in several cellular processes, including inflammation, cell differentiation and tumor cell migration. Multiple pseudogenes of this gene have been identified. Alternative splicing results in multiple transcript variants that encode the same protein.

Classification:

Primary antibody

Alternative names:

HMGB1; HMG1; High mobility group protein B1; High mobility group protein 1; HMG-1

Species reactivity:

Human;Mouse;Rat

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from human HMGB1. AA range:131-180

Concentration:

1 mg/ml

Molecular weight:

24894

Applications:

WB, IHC-p, IF, IP, ELISA

Storage:

-20°C for one year

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