Background:

Growth factor receptor-bound protein 14 belongs to a small family of adapter proteins that are known to interact with a number of receptor tyrosine kinases and signaling molecules. GRB14 encodes a growth factor receptor-binding protein that interacts with insulin receptors and insulin-like growth-factor receptors. Growth factor receptor-bound protein 14 likely has an inhibitory effect on receptor tyrosine kinase signaling and, in particular, on insulin receptor signaling. GRB14 may play a role in signaling pathways that regulate growth and metabolism. Alternative splicing results in multiple transcript variants.

Classification:

Primary antibody

Alternative names:

GRB14; Growth factor receptor-bound protein 14; GRB14 adapter protein

Species reactivity:

Human;Mouse;Rat

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from human GRB14. AA range:81-130

Concentration:

1 mg/ml

Molecular weight:

60988

Applications:

WB, IHC-p, ELISA

Storage:

-20°C for one year

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