Background:

Granzyme K is a member of a group of related serine proteases from the cytoplasmic granules of cytotoxic lymphocytes. Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the remarkable ability to recognize, bind, and lyse specific target cells. They are thought to protect their host by lysing cells bearing on their surface ‘nonself’ antigens, usually peptides or proteins resulting from infection by intracellular pathogens. The protein described here lacks consensus sequences for N-glycosylation present in other granzymes.

Classification:

Primary antibody

Alternative names:

GZMK; TRYP2; Granzyme K; Fragmentin-3; Granzyme-3; NK-tryptase-2; NK-Tryp-2

Species reactivity:

Human;Mouse;Rat

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from human GRAK. AA range:61-110

Concentration:

1 mg/ml

Molecular weight:

28882

Applications:

WB, IHC-p, IF, ELISA

Storage:

-20°C for one year

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