Background:

GPR143 encodes a protein that binds to heterotrimeric G proteins and is targeted to melanosomes in pigment cells. This protein is thought to be involved in intracellular signal transduction mechanisms. Mutations in GPR143 cause ocular albinism type 1, also referred to as Nettleship-Falls type ocular albinism, a severe visual disorder. A related pseudogene has been identified on chromosome Y.

Classification:

Primary antibody

Alternative names:

GPR143; OA1; G-protein coupled receptor 143; Ocular albinism type 1 protein

Species reactivity:

Human;Mouse

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from human GPR143. AA range:151-200

Concentration:

1 mg/ml

Molecular weight:

43878

Applications:

IF, ELISA

Storage:

-20°C for one year

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