Background:

GLRB encodes the beta subunit of the glycine receptor, which is a pentamer composed of alpha and beta subunits. The receptor functions as a neurotransmitter-gated ion channel, which produces hyperpolarization via increased chloride conductance due to the binding of glycine to the receptor. Mutations in this gene cause startle disease, also known as hereditary hyperekplexia or congenital stiff-person syndrome, a disease characterized by muscular rigidity. Alternative splicing results in multiple transcript variants.

Classification:

Primary antibody

Alternative names:

GLRB; Glycine receptor subunit beta; Glycine receptor 58 kDa subunit

Species reactivity:

Human;Mouse;Rat

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from human GLRB. AA range:211-260

Concentration:

1 mg/ml

Molecular weight:

56122

Applications:

WB, ELISA

Storage:

-20°C for one year

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