Background:

GANAB encodes the alpha subunit of glucosidase II and a member of the glycosyl hydrolase 31 family of proteins. The heterodimeric enzyme glucosidase II plays a role in protein folding and quality control by cleaving glucose residues from immature glycoproteins in the endoplasmic reticulum. Expression of the encoded protein is elevated in lung tumor tissue and in response to UV irradiation. Mutations in this gene cause autosomal-dominant polycystic kidney and liver disease.

Classification:

Primary antibody

Alternative names:

GANAB; G2AN; KIAA0088; Neutral alpha-glucosidase AB; Alpha-glucosidase 2; Glucosidase II subunit alpha

Species reactivity:

Human;Mouse

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from human GANAB. AA range:242-291

Concentration:

1 mg/ml

Molecular weight:

106874

Applications:

WB, IHC-p, ELISA

Storage:

-20°C for one year

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