Background:

GIPR encodes Gastric inhibitory polypeptide receptor for gastric inhibitory polypeptide (GIP), which was originally identified as an activity in gut extracts that inhibited gastric acid secretion and gastrin release, but subsequently was demonstrated to stimulate insulin release in the presence of elevated glucose. Mice lacking GIPR exhibit higher blood glucose levels with impaired initial insulin response after oral glucose load. Defect in GIPR thus may contribute to the pathogenesis of diabetes.

Classification:

Primary antibody

Alternative names:

GIPR; Gastric inhibitory polypeptide receptor; GIP-R; Glucose-dependent insulinotropic polypeptide receptor

Species reactivity:

Human

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from human GIPR. AA range:93-142

Concentration:

1 mg/ml

Molecular weight:

53157

Applications:

WB, IHC-p, IF, ELISA

Storage:

-20°C for one year

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