Background:

GDF9 encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. Growth/differentiation factor 9 regulates ovarian function. Reduced expression of GDF9 may be associated with polycystic ovary syndrome and mutations in this gene may be more common in mothers of dizygotic twins.

Classification:

Primary antibody

Alternative names:

GDF9; Growth/differentiation factor 9; GDF-9

Species reactivity:

Human

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from human GDF-9. AA range:273-322

Concentration:

1 mg/ml

Molecular weight:

51444

Applications:

WB, IHC-p, ELISA

Storage:

-20°C for one year

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