Background:

Glucagon encoded by GCG is actually a preproprotein that is cleaved into four distinct mature peptides. One of these, glucagon, is a pancreatic hormone that counteracts the glucose-lowering action of insulin by stimulating glycogenolysis and gluconeogenesis. Glucagon is a ligand for a specific G-protein linked receptor whose signalling pathway controls cell proliferation. Two of the other peptides are secreted from gut endocrine cells and promote nutrient absorption through distinct mechanisms. Finally, the fourth peptide is similar to glicentin, an active enteroglucagon.

Classification:

Primary antibody

Alternative names:

GCG; Glucagon

Species reactivity:

Human;Mouse;Rat;Monkey

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from human Glucagon. AA range:61-110

Concentration:

1 mg/ml

Molecular weight:

20909

Applications:

WB, IHC-p, IF, ELISA

Storage:

-20°C for one year

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