Background:

GATA4 encodes a member of the GATA family of zinc-finger transcription factors. Members of this family recognize the GATA motif which is present in the promoters of many genes. Transcription factor GATA-4 is thought to regulate genes involved in embryogenesis and in myocardial differentiation and function, and is necessary for normal testicular development. Mutations in GATA4 have been associated with cardiac septal defects. Additionally, alterations in gene expression have been associated with several cancer types. Alternative splicing results in multiple transcript variants.

Classification:

Primary antibody

Alternative names:

GATA4; Transcription factor GATA-4; GATA-binding factor 4

Species reactivity:

Human;Mouse;Rat

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from human GATA4. AA range:71-120

Concentration:

1 mg/ml

Molecular weight:

44627

Applications:

WB, IHC-p, IF, ELISA

Storage:

-20°C for one year

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