Background:

GPRASP1 (G protein-coupled receptor associated sorting protein 1) encodes a member of the GPRASP (G protein-coupled receptor associated sorting protein) family. The protein may modulate lysosomal sorting and functional down-regulation of a variety of G-protein coupled receptors. It targets receptors for degradation in lysosomes. The receptors interacting with this sorting protein include D2 dopamine receptor (DRD2), delta opioid receptor (OPRD1), beta-2 adrenergic receptor (ADRB2), D4 dopamine receptor (DRD4) and cannabinoid 1 receptor (CB1R). Multiple alternatively spliced transcript variants encoding the same protein have been identified.

Classification:

Primary antibody

Alternative names:

GPRASP1; GASP; KIAA0443; G-protein coupled receptor-associated sorting protein 1; GASP-1

Species reactivity:

Human

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from human GASP1. AA range:741-790

Concentration:

1 mg/ml

Molecular weight:

156865

Applications:

IHC-p, IF, ELISA

Storage:

-20°C for one year

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