Background:

PMP22 (peripheral myelin protein 22) encodes an integral membrane protein that is a major component of myelin in the peripheral nervous system. Studies suggest two alternately used promoters drive tissue-specific expression. Various mutations of PMP22 are causes of Charcot-Marie-Tooth disease Type IA, Dejerine-Sottas syndrome, and hereditary neuropathy with liability to pressure palsies. Alternative splicing results in multiple transcript variants.

Classification:

Primary antibody

Alternative names:

PMP22; GAS3; Peripheral myelin protein 22; PMP-22; Growth arrest-specific protein 3; GAS-3

Species reactivity:

Human;Mouse;Rat

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from human PMP22. AA range:111-160

Concentration:

1 mg/ml

Molecular weight:

17891

Applications:

WB, IHC-p, ELISA

Storage:

-20°C for one year

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