Background:

This intronless gene FZD8 (frizzled class receptor 8) is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. FZD8 is highly expressed in two human cancer cell lines, indicating that it may play a role in several types of cancer. The crystal structure of the extracellular cysteine-rich domain of a similar mouse protein has been determined.

Classification:

Primary antibody

Alternative names:

FZD8; Frizzled-8; Fz-8; hFz8

Species reactivity:

Human;Mouse;Rat

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from human FZD8. AA range:486-535

Concentration:

1 mg/ml

Molecular weight:

73300

Applications:

WB, IHC-p, ELISA

Storage:

-20°C for one year

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