Background:

Members of the frizzled gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. Frizzled-7 contains an N-terminal signal sequence, 10 cysteine residues typical of the cysteine-rich extracellular domain of Fz family members, 7 putative transmembrane domains, and an intracellular C-terminal tail with a PDZ domain-binding motif. FZD7 expression may downregulate APC function and enhance beta-catenin-mediated signals in poorly differentiated human esophageal carcinomas.

Classification:

Primary antibody

Alternative names:

FZD7; Frizzled-7; Fz-7; hFz7; FzE3

Species reactivity:

Human;Mouse

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from human FZD7. AA range:45-94

Concentration:

1 mg/ml

Molecular weight:

63620

Applications:

WB, IF, ELISA

Storage:

-20°C for one year

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