Background:

FZD4 (frizzled class receptor 4) is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. This protein may play a role as a positive regulator of the Wingless type MMTV integration site signaling pathway. A transcript variant retaining intronic sequence and encoding a shorter isoform has been described, however, its expression is not supported by other experimental evidence.

Classification:

Primary antibody

Alternative names:

FZD4; Frizzled-4; Fz-4; hFz4; FzE4; CD antigen CD344

Species reactivity:

Human;Mouse;Rat

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from human FZD4. AA range:131-180

Concentration:

1 mg/ml

Molecular weight:

59881

Applications:

IF, ELISA

Storage:

-20°C for one year

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