Background:

EFEMP1 encodes a member of the fibulin family of extracellular matrix glycoproteins. Like all members of this family, the EGF containing fibulin like extracellular matrix protein 1 contains tandemly repeated epidermal growth factor-like repeats followed by a C-terminus fibulin-type domain. This gene is upregulated in malignant gliomas and may play a role in the aggressive nature of these tumors. Mutations in this gene are associated with Doyne honeycomb retinal dystrophy. Alternatively spliced transcript variants that encode the same protein have been described.

Classification:

Primary antibody

Alternative names:

EFEMP1; FBLN3; FBNL; EGF-containing fibulin-like extracellular matrix protein 1; Extracellular protein S1-5; Fibrillin-like protein; Fibulin-3; FIBL-3

Species reactivity:

Human;Mouse;Rat

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from human EFEMP1. AA range:111-160

Concentration:

1 mg/ml

Molecular weight:

54641

Applications:

WB, IHC-p, ELISA

Storage:

-20°C for one year

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