Background:

The protein encoded by FGF18 (fibroblast growth factor 18) is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth, and invasion. It has been shown in vitro that this protein is able to induce neurite outgrowth in PC12 cells. Studies of the similar proteins in mouse and chick suggested that this protein is a pleiotropic growth factor that stimulates proliferation in a number of tissues, most notably the liver and small intestine. Knockout studies of the similar gene in mice implied the role of this protein in regulating proliferation and differentiation of midline cerebellar structures.

Classification:

Primary antibody

Alternative names:

FGF18; Fibroblast growth factor 18; FGF-18; zFGF5

Species reactivity:

Human

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from human FGF18. AA range:151-200

Concentration:

1 mg/ml

Molecular weight:

23989

Applications:

IHC-p, IF, ELISA

Storage:

-20°C for one year

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