Background:

FBXO7 (F-box protein 7) encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by FBXO7 belongs to the Fbxs class and it may play a role in regulation of hematopoiesis. Alternatively spliced transcript variants of FBXO7 have been identified with the full-length natures of only some variants being determined.

Classification:

Primary antibody

Alternative names:

FBXO7 FBX7

Species reactivity:

Human

Host:

Rabbit

Isotype:

IgG

Immunogen:

Synthetic peptide from human protein at AA range: 371-420

Concentration:

1 mg/ml

Molecular weight:

58503

Applications:

WB, ELISA

Storage:

-20°C for one year

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