Background:

Fas-activated serine/threonine kinase encoded by FASTK is a member of the serine/threonine protein kinase family. This kinase was shown to be activated rapidly during Fas-mediated apoptosis in Jurkat cells. In response to Fas receptor ligation, it phosphorylates TIA1, an apoptosis-promoting nuclear RNA-binding protein. The encoded protein is a strong inducer of lymphocyte apoptosis. Two transcript variants encoding different isoforms have been found for this gene. Other variants exist, but their full-length natures have not yet been determined.

Classification:

Primary antibody

Alternative names:

FASTK; Fas-activated serine/threonine kinase; FAST kinase

Species reactivity:

Human;Mouse;Rat

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from human FAST. AA range:361-410

Concentration:

1 mg/ml

Molecular weight:

61104

Applications:

WB, ELISA

Storage:

-20°C for one year

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