Background:

Interaction of Fas ligand (TNFSF6) with the FAS antigen (TNFRSF6) mediates programmed cell death, also called apoptosis, in a number of organ systems. The Fas associated factor 1 encoded by FAF1 binds to FAS antigen and can initiate apoptosis or enhance apoptosis initiated through FAS antigen. Initiation of apoptosis by the protein encoded by FAF1 requires a ubiquitin-like domain but not the FAS-binding domain.

Classification:

Primary antibody

Alternative names:

FAF1; UBXD12; UBXN3A; CGI-03; FAS-associated factor 1; hFAF1; UBX domain-containing protein 12; UBX domain-containing protein 3A

Species reactivity:

Human;Mouse;Rat

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from human FAF1. AA range:531-580

Concentration:

1 mg/ml

Molecular weight:

73954

Applications:

WB, ELISA

Storage:

-20°C for one year

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