Background:

CBFA2T3 (CBFA2/RUNX1 translocation partner 3) encodes a member of the myeloid translocation gene family which interact with DNA-bound transcription factors and recruit a range of corepressors to facilitate transcriptional repression. The t (16; 21) (q24; q22) translocation is one of the less common karyotypic abnormalities in acute myeloid leukemia. The translocation produces a chimeric gene made up of the 5'-region of the runt-related transcription factor 1 gene fused to the 3'-region of CBFA2T3. CBFA2T3 is also a putative breast tumor suppressor. Alternative splicing results in transcript variants.

Classification:

Primary antibody

Alternative names:

CBFA2T3; MTG16; MTGR2; ZMYND4; Protein CBFA2T3; MTG8-related protein 2; Myeloid translocation gene on chromosome 16 protein; hMTG16; Zinc finger MYND domain-containing protein 4

Species reactivity:

Human;Mouse

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from human MTG16. AA range:261-310

Concentration:

1 mg/ml

Molecular weight:

71192

Applications:

IHC-p, ELISA

Storage:

-20°C for one year

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