Background:

The protein encoded by EDNRB (endothelin receptor type B) is a G protein-coupled receptor which activates a phosphatidylinositol-calcium second messenger system. Its ligand, endothelin, consists of a family of three potent vasoactive peptides: eT1, ET2, and ET3. Studies suggest that the multigenic disorder, Hirschsprung disease type 2, is due to mutations in the endothelin receptor type B gene. Alternatively spliced transcript variants encoding different isoforms have been found for EDNRB.

Classification:

Primary antibody

Alternative names:

Endothelin B receptor (ET-B) (ET-BR) (Endothelin receptor non-selective type)

Species reactivity:

Human

Host:

Rabbit

Isotype:

IgG

Immunogen:

Synthesized peptide derived from ETBR at AA range: 31-80

Concentration:

1 mg/ml

Molecular weight:

49644

Applications:

WB, IHC-p, ELISA

Storage:

-20°C for one year

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