Background:

EDN1 encodes a preproprotein that is proteolytically processed to generate a secreted peptide that belongs to the endothelin/sarafotoxin family. This peptide is a potent vasoconstrictor and its cognate receptors are therapeutic targets in the treatment of pulmonary arterial hypertension. Aberrant expression of this gene may promote tumorigenesis. Alternative splicing results in multiple transcript variants.

Classification:

Primary antibody

Alternative names:

EDN1; Endothelin-1; Preproendothelin-1; PPET1

Species reactivity:

Human

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from the Internal region of human EDN1. AA range:131-180

Concentration:

1 mg/ml

Molecular weight:

24425

Applications:

WB, IHC-p, ELISA

Storage:

-20°C for one year

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