Background:

EMX2 encodes a homeobox-containing transcription factor that is the homolog to the empty spiracles gene in Drosophila. Research on EMX2 in humans has focused on its expression in three tissues: dorsal telencephalon, olfactory neuroepithelium, and urogenetial system. It is expressed in the dorsal telencephalon during development in a low rostral-lateral to high caudal-medial gradient and is proposed to pattern the neocortex into defined functional areas. It is also expressed in embryonic and adult olfactory neuroepithelia where it complexes with eukaryotic translation initiation factor 4E (eIF4E) and possibly regulates mRNA transport or translation. In the developing urogenital system, it is expressed in epithelial tissues and is negatively regulated by HOXA10. Alternative splicing results in multiple transcript variants encoding distinct proteins.

Classification:

Primary antibody

Alternative names:

EMX2; Homeobox protein EMX2; Empty spiracles homolog 2; Empty spiracles-like protein 2

Species reactivity:

Human;Mouse

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from human EMX2. AA range:91-140

Concentration:

1 mg/ml

Molecular weight:

28303

Applications:

IHC-p, ELISA

Storage:

-20°C for one year

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