Background:

ADGRE3 (adhesion G protein-coupled receptor E3) encodes a member of the class B seven-span transmembrane (TM7) receptor family expressed predominantly by cells of the immune system. Family members are characterized by an extended extracellular region with a variable number of N-terminal epidermal growth factor (EGF)-like domains coupled to a TM7 domain via a mucin-like spacer domain. ADGRE3 is closely linked to the gene encoding egf-like molecule containing mucin-like hormone receptor 2 on chromosome 19. This protein may play a role in myeloid-myeloid interactions during immune and inflammatory responses. Alternative splicing results in multiple transcript variants encoding different isoforms.

Classification:

Primary antibody

Alternative names:

EMR3; EGF-like module-containing mucin-like hormone receptor-like 3; EGF-like module receptor 3

Species reactivity:

Human

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from human EMR3. AA range:603-652

Concentration:

1 mg/ml

Molecular weight:

72593

Applications:

WB, IF, ELISA

Storage:

-20°C for one year

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