Background:

EME1 encodes essential meiotic structure-specific endonuclease 1 that complexes with methyl methanesulfonate-sensitive UV-sensitive 81 protein to form an endonuclease complex. The encoded protein interacts with specifc DNA structures including nicked Holliday junctions, 3'-flap structures and aberrant replication fork structures. This protein may be involved in repairing DNA damage and in maintaining genomic stability. Alternative splicing results in multiple transcript variants.

Classification:

Primary antibody

Alternative names:

EME1; MMS4; Crossover junction endonuclease EME1; MMS4 homolog; hMMS4

Species reactivity:

Human

Host:

Rabbit

Isotype:

IgG

Immunogen:

Synthesized peptide derived from Eme1 . at AA range: 250-330

Concentration:

1 mg/ml

Molecular weight:

63252

Applications:

WB, ELISA

Storage:

-20°C for one year

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