Background:

KLF1 encodes a hematopoietic-specific transcription factor that induces high-level expression of adult beta-globin and other erythroid genes. The zinc-finger protein binds to the DNA sequence CCACACCCT found in the beta hemoglobin promoter. Heterozygous loss-of-function mutations in this gene result in the dominant In(Lu) blood phenotype.

Classification:

Primary antibody

Alternative names:

KLF1; EKLF; Krueppel-like factor 1; Erythroid krueppel-like transcription factor; EKLF

Species reactivity:

Human

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from human KLF1 around the non-acetylation site of Lys274. AA range:231-280

Concentration:

1 mg/ml

Molecular weight:

38221

Applications:

WB, ELISA

Storage:

-20°C for one year

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