Background:

Eukaryotic translation initiation factor 2B subunit gamma encoded by EIF2B3 is one of the subunits of initiation factor eIF2B, which catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP. It has also been found to function as a cofactor of hepatitis C virus internal ribosome entry site-mediated translation. Mutations in EIF2B3 have been associated with leukodystrophy with vanishing white matter. Alternatively spliced transcript variants encoding different isoforms have been found for EIF2B3.

Classification:

Primary antibody

Alternative names:

EIF2B3; Translation initiation factor eIF-2B subunit gamma; eIF-2B GDP-GTP exchange factor subunit gamma

Species reactivity:

Human;Mouse

Host:

Rabbit

Isotype:

IgG

Immunogen:

Synthesized peptide derived from eIF2Bγ . at AA range: 240-320

Concentration:

1 mg/ml

Molecular weight:

50240

Applications:

WB, ELISA

Storage:

-20°C for one year

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