Background:

The protein encoded by EDA (ectodysplasin A) is a type II membrane protein that can be cleaved by furin to produce a secreted form. The encoded protein, which belongs to the tumor necrosis factor family, acts as a homotrimer and may be involved in cell-cell signaling during the development of ectodermal organs. Defects in EDA are a cause of ectodermal dysplasia, anhidrotic, which is also known as X-linked hypohidrotic ectodermal dysplasia. Several transcript variants encoding many different isoforms have been found for EDA.

Classification:

Primary antibody

Alternative names:

EDA; ED1; EDA2; Ectodysplasin-A; Ectodermal dysplasia protein; EDA protein

Species reactivity:

Human;Mouse

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from the Internal region of human EDA. AA range:120-170

Concentration:

1 mg/ml

Molecular weight:

43010

Applications:

WB, IHC-p, ELISA

Storage:

-20°C for one year

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