Background:

NR2F6, also known as Nuclear receptor subfamily 2 group F member 6, is a nuclear protein belonging to the nuclear hormone receptor family and NR2 subfamily with a nuclear receptor DNA-binding domain. NR2F6 is a nuclear receptor involved in action regulation of the transcription of the GNRH1 gene. It binds to the TGACCT repeat motif enhancing the renin gene and thus acting as a negative modulator of renin gene transcription. NR2F6 is required early in the development of the locus ceruleus (LC), thus in some way contributing to the regulation of the forebrain clock, at least in part, through targeted release of noradrenalin into the cortical area.

Classification:

Primary antibody

Alternative names:

NR2F6; EAR2; ERBAL2; Nuclear receptor subfamily 2 group F member 6; V-erbA-related protein 2; EAR-2

Species reactivity:

Human;Mouse;Rat

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from human NR2F6. AA range:11-60

Concentration:

1 mg/ml

Molecular weight:

42979

Applications:

WB, IHC-p, IF, ELISA

Storage:

-20°C for one year

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