Background:

DUS2 (dihydrouridine synthase 2) encodes a cytoplasmic protein that catalyzes the conversion of uridine residues to dihydrouridine in the D-loop of tRNA. The resulting modified bases confer enhanced regional flexibility to tRNA. The encoded protein may increase the rate of translation by inhibiting an interferon-induced protein kinase. DUS2 has been implicated in pulmonary carcinogenesis. Alternatively spliced transcript variants have been described for DUS2.

Classification:

Primary antibody

Alternative names:

DUS2L; DUS2; tRNA-dihydrouridine(20) synthase [NAD(P)+]-like; Up-regulated in lung cancer protein 8; URLC8; tRNA-dihydrouridine synthase 2-like; hDUS2

Species reactivity:

Human;Mouse

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from human DUS2L. AA range:421-470

Concentration:

1 mg/ml

Molecular weight:

55050

Applications:

WB, IHC-p, ELISA

Storage:

-20°C for one year

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