Background:

DOCK1 encodes a member of the dedicator of cytokinesis protein family. Dedicator of cytokinesis proteins act as guanine nucleotide exchange factors for small Rho family G proteins. Dedicator of cytokinesis protein 1 regulates the small GTPase Rac, thereby influencing several biological processes, including phagocytosis and cell migration. Overexpression of this gene has also been associated with certain cancers. Alternative splicing results in multiple transcript variants.

Classification:

Primary antibody

Alternative names:

DOCK1; Dedicator of cytokinesis protein 1; 180 kDa protein downstream of CRK; DOCK180

Species reactivity:

Human;Mouse

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from human DOCK1. AA range:1661-1710

Concentration:

1 mg/ml

Molecular weight:

215376

Applications:

WB, ELISA

Storage:

-20°C for one year

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