Background:

POLE (DNA polymerase epsilon, catalytic subunit) encodes the catalytic subunit of DNA polymerase epsilon. The enzyme is involved in DNA repair and chromosomal DNA replication. Mutations in POLE have been associated with colorectal cancer 12 and facial dysmorphism, immunodeficiency, livedo, and short stature.

Classification:

Primary antibody

Alternative names:

POLE; POLE1; DNA polymerase epsilon catalytic subunit A; DNA polymerase II subunit A

Species reactivity:

Human;Rat

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from human POLE1. AA range:1261-1310

Concentration:

1 mg/ml

Molecular weight:

261518

Applications:

IHC-p, ELISA

Storage:

-20°C for one year

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