Background:

POLG2 encodes the processivity subunit of the mitochondrial DNA polymerase gamma. The DNA polymerase gamma 2, accessory subunit forms a heterotrimer containing one catalytic subunit and two processivity subunits. This protein enhances DNA binding and promotes processive DNA synthesis. Mutations in this gene result in autosomal dominant progressive external ophthalmoplegia with mitochondrial DNA deletions.

Classification:

Primary antibody

Alternative names:

POLG2; MTPOLB; DNA polymerase subunit gamma-2; mitochondrial; DNA polymerase gamma accessory 55 kDa subunit; p55; Mitochondrial DNA polymerase accessory subunit; MtPolB; PolG-beta

Species reactivity:

Human

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from human POLG2. AA range:291-340

Concentration:

1 mg/ml

Molecular weight:

54911

Applications:

IHC-p, ELISA

Storage:

-20°C for one year

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