Background:

The protein encoded by KRT2 is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is expressed largely in the upper spinous layer of epidermal keratinocytes and mutations in KRT2 have been associated with bullous congenital ichthyosiform erythroderma. The type II cytokeratins are clustered in a region of chromosome 12q12-q13.

Classification:

Primary antibody

Alternative names:

KRT2; KRT2A; KRT2E; Keratin, type II cytoskeletal 2 epidermal; Cytokeratin-2e; CK-2e; Epithelial keratin-2e; Keratin-2 epidermis; Keratin-2e; K2e; Type-II keratin Kb2; KRT76; KRT2B; KRT2P; Keratin, ty

Species reactivity:

Human;Mouse;Rat

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized Acetyl-peptide derived from human Keratin-pan around the Acetylation site of Lys194. AA range:151-200

Concentration:

1 mg/ml

Molecular weight:

65433/65841/64417/62378/60045/60067/60025/57292/55877/58923/57865/59560/57836/53704/64842

Applications:

WB, ELISA

Storage:

-20°C for one year

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