Background:

CYSLTR1 encodes a member of the G-protein coupled receptor 1 family. Cysteinyl leukotriene receptor 1 is a receptor for cysteinyl leukotrienes, and is involved in mediating bronchoconstriction via activation of a phosphatidylinositol-calcium second messenger system. Activation of the encoded receptor results in contraction and proliferation of bronchial smooth muscle cells, eosinophil migration, and damage to the mucus layer in the lung. Upregulation of CYSLTR1 is associated with asthma and dysregulation may also be implicated in cancer. Alternative splicing results in multiple transcript variants.

Classification:

Primary antibody

Alternative names:

CYSLTR1; CYSLT1; Cysteinyl leukotriene receptor 1; CysLTR1; Cysteinyl leukotriene D4 receptor; LTD4 receptor; G-protein coupled receptor HG55; HMTMF81

Species reactivity:

Human

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from human CYSLTR1. AA range:131-180

Concentration:

1 mg/ml

Molecular weight:

38541

Applications:

WB, IF, ELISA

Storage:

-20°C for one year

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