Background:

CYP2C18 encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. Cytochrome P450 2C8/9/18/19 localizes to the endoplasmic reticulum but its specific substrate has not yet been determined. CYP2C18 is located within a cluster of cytochrome P450 genes on chromosome 10q24. An additional gene, CYP2C17, was once thought to exist; however, CYP2C17 is now considered an artefact based on a chimera of CYP2C18 and CYP2C19. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Classification:

Primary antibody

Alternative names:

CYP2C8; Cytochrome P450 2C8; CYPIIC8; Cytochrome P450 IIC2; Cytochrome P450 MP-12; Cytochrome P450 MP-20; Cytochrome P450 form 1; S-mephenytoin 4-hydroxylase; CYP2C9; CYP2C10; Cytochrome P450 2C9; (R)

Species reactivity:

Human

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from human Cytochrome P450 2C8/9/18/19. AA range:111-160

Concentration:

1 mg/ml

Molecular weight:

55711

Applications:

WB, IHC-p, IF, ELISA

Storage:

-20°C for one year

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