Background:

CUL3 encodes a member of the cullin protein family. Cullin 3 plays a critical role in the polyubiquitination and subsequent degradation of specific protein substrates as the core component and scaffold protein of an E3 ubiquitin ligase complex. Complexes including the encoded protein may also play a role in late endosome maturation. Mutations in this gene are a cause of type 2E pseudohypoaldosteronism. Alternatively spliced transcript variants encoding multiple isoforms have been observed for CUL3.

Classification:

Primary antibody

Alternative names:

CUL3; KIAA0617; Cullin-3; CUL-3

Species reactivity:

Human;Mouse

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from human Cullin 3. AA range:1-50

Concentration:

1 mg/ml

Molecular weight:

88930

Applications:

WB, IHC-p, ELISA

Storage:

-20°C for one year

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