Background:

Cubilin (CUBN) acts as a receptor for intrinsic factor-vitamin B12 complexes. The role of receptor is supported by the presence of 27 CUB domains. Cubulin is located within the epithelium of intestine and kidney. Mutations in CUBN may play a role in autosomal recessive megaloblastic anemia.

Classification:

Primary antibody

Alternative names:

CUBN; IFCR; Cubilin; 460 kDa receptor; Intestinal intrinsic factor receptor; Intrinsic factor-cobalamin receptor; Intrinsic factor-vitamin B12 receptor

Species reactivity:

Human

Host:

Rabbit

Isotype:

IgG

Immunogen:

Synthesized peptide derived from the N-terminal region of human Cubilin.

Concentration:

1 mg/ml

Molecular weight:

398726

Applications:

IHC-p, WB, ELISA

Storage:

-20°C for one year

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