Background:

COP9 signalosome subunit 3 encoded by COPS3 possesses kinase activity that phosphorylates regulators involved in signal transduction. It phosphorylates I kappa-Balpha, p105, and c-Jun. It acts as a docking site for complex-mediated phosphorylation. The gene is located within the Smith-Magenis syndrome region on chromosome 17. Several transcript variants encoding different isoforms have been found for COPS3.

Classification:

Primary antibody

Alternative names:

COPS3; CSN3; COP9 signalosome complex subunit 3; SGN3; Signalosome subunit 3; JAB1-containing signalosome subunit 3

Species reactivity:

Human;Mouse;Rat

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from human JAB1. AA range:374-423

Concentration:

1 mg/ml

Molecular weight:

47873

Applications:

WB, IHC-p, IF, ELISA

Storage:

-20°C for one year

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